Fair value liabilities level 3 to level 2 transfers amount.
Fair Value Liabilities Level3 To Level2 Transfers Amount
Transfer of liabilities from level 3 to level 2
Entity Address, City or Town
Entity Address, City or Town
Entity Ex Transition Period
Entity Ex Transition Period
Fair Value Disclosures [Abstract]
Fair Value, Inputs, Level 1 [Member]
Quoted prices in Active Market for Identical Assets (Level 1)
Schedule of Accrued Liabilities [Table Text Block]
Schedule of accrued expenses
Stock Issued During Period, Value, New Issues
Public offering of common stock, net of issuance costs
Aggregate purchase price of common stock
Net Cash Provided by (Used in) Financing Activities [Abstract]
Financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Amendment Flag
Amendment Flag
California Institute For Regenerative Medicine [Member]
California Institute for Regenerative Medicine
California institute for regenerative medicine .
Capital Expenditures Incurred but Not yet Paid
Purchases of property and equipment in accounts payable
Other Long-Term Investments [Member]
Long-term Investments [Member]
Payments to Employees
Wages per employee
Collaborative arrangement aggregate payments receivable.
Collaborative Arrangement Aggregate Payments Receivable
Aggregate research and development fees payments receivable
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets
Short-Term Investments [Abstract]
Option exercise payment.
Option Exercise Payment
Option exercise payment
Document Quarterly Report
Document Quarterly Report
Achievement of stock price appreciation milestone
Achievement of stock price appreciation milestone
Increase decrease in right-of-use assets and lease liabilities, net.
Increase Decrease In Right Of Use Assets And Lease Liabilities Net
Right-of-use assets and lease liabilities, net
Available For Sale Securities Debt Security
Available For Sale Securities Debt Security
Fair Value Assumptions Expected Volatility Rate 1.
Fair Value Assumptions Expected Volatility Rate1
Expected volatility
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
Earnings Per Share, Policy [Policy Text Block]
Net Loss per Common Share
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents
Statement [Table]
Statement [Table]
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Equity Option [Member]
2022 Stock Option and Incentive Plan
January Twenty Twenty One Public Equity Offering [Member]
January Twenty Twenty One Public Equity Offering.
January 2021 Public Offering
London Interbank Offered Rate (LIBOR) [Member]
LIBOR
Preferred Stock, Shares Outstanding
Preferred stock, outstanding shares
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Balance at the end of the period
Balance at the beginning of the period
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested
Candidate Two [Member]
Candidate 2
Candidate two.
Enterprise value milestone payments contingent consideration.
Enterprise Value Milestone Payments Contingent Consideration [Member]
Enterprise value milestone payments contingent consideration
Shares, Issued
Balance (in shares)
Balance (in shares)
Product and Service [Axis]
Product and Service
Ono Letter Agreement.
Ono Letter Agreement [Member]
Ono Letter Agreement
No definition available.
Collaboration And License Agreements Disclosure [Abstract]
Short-term leases term excluded from calculation of right of use of assets and lease liabilities.
Short Term Leases Term Excluded From Calculation Of Right Of Use Of Assets And Lease Liabilities
Short-term leases term excluded from calculation of ROU and lease liabilities
Lessee, Operating Leases [Text Block]
Leases
Stock price appreciation milestones
Stock price appreciation milestones, non current portion.
Stock Price Appreciation Milestones Liabilities Non Current
Stock-based compensation, shares
Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture
Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture, Total
Operating Lease, Weighted Average Remaining Lease Term
Remaining weighted-average lease term
Liabilities and Equity
Total liabilities and stockholders’ equity
Plan Name [Domain]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Transaction price of agreement.
Transaction Price Of Agreement
Transaction price of the agreement
Investments [Abstract]
Deferred Revenue
Deferred revenue
Deferred Revenue, Total
Repayment percentage of award amount.
Repayment Percentage Of Award Amount
Repayment percentage of award amount
Sale of Stock [Domain]
Sale of Stock
Liabilities, Current
Total current liabilities
Number of disbursements receivable upon execution of award.
Number Of Disbursements Receivable Upon Execution Of Award
Number of disbursement receivable upon the execution of the award
Expected ressarch services period
Expected Ressarch Services Period
Expected ressarch services period.
2025
Lessee, Operating Lease, Liability, to be Paid, Year Three
Contract with Customer, Asset, after Allowance for Credit Loss, Noncurrent
Collaboration contract asset
Collaboration contract assets
Contract with Customer, Asset, after Allowance for Credit Loss, Noncurrent, Total
Fair Value, Recurring [Member]
Fair Value Measurements Recurring
Amended MSK license member.
Amended M S K License [Member]
Amended MSK License
Short-Term Lease, Cost
Total short-term lease expense
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses
Liquidity.
Liquidity Policy [Text Block]
Going Concern Assessment
Increase (Decrease) in Contract with Customer, Liability
Deferred revenue
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Other Noncurrent Assets [Member]
Non-current Assets [Member]
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease liabilities, weighted-average discount rate
Revenue, Product and Service [Extensible Enumeration]
Type of Revenue [Extensible List]
Variable Rate [Axis]
Variable Rate
Entity Small Business
Entity Small Business
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Sublicense Consideration Represents an Asset Under ASC, Other Assets and Deferred Costs
Sublicense Consideration Represents an Asset Under ASC, Other Assets and Deferred Costs
Sublicense Consideration Represents an Asset Under ASC, Other Assets and Deferred Costs
Investments [Domain]
Investments
Convertible preferred stock and stockholders' equity.
Convertible Preferred Stock And Stockholders Equity Disclosure [Abstract]
Total current assets
Assets, Current
Stock price appreciation milestone, expense
Stock Price Appreciation Milestone Expense
Stock price appreciation milestone expense.
Other than Temporary Impairment, Credit Losses Recognized in Earnings, Credit Losses on Debt Securities Held
Available-for-sale securities, recognition of expected credit losses
Other than Temporary Impairment, Credit Losses Recognized in Earnings, Credit Losses on Debt Securities Held, Beginning Balance
Other than Temporary Impairment, Credit Losses Recognized in Earnings, Credit Losses on Debt Securities Held, Ending Balance
Remaining in 2022
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Janssen Biotech Inc.
Janssen Biotech Inc [Member]
Janssen Biotech Inc
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic
City Area Code
City Area Code
Regulatory and sales milestone payment
Regulatory And Sales Milestone Payment
Development, regulatory, and sales milestones
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Cancelled
Award agreement executed date.
Award Agreement Executed Date
Award agreement executed date
Share-Based Payment Arrangement [Abstract]
Silicon valley bank.
Silicon Valley Bank [Member]
Silicon Valley Bank
Private Placement [Member]
Private Placement
Document Period End Date
Document Period End Date
Payments of Stock Issuance Costs
Costs related to equity offering
Investment maturity date range.
Investment Maturity Date Range
Maturity (in years)
Lessee, Operating Lease, Renewal Term
Renewal term
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Contract with Customer, Liability, Noncurrent
Deferred revenue, net of current portion
Statistical Measurement [Axis]
Statistical Measurement
Common stock multiple.
Common Stock Multiple
Common stock multiple
Estimated Fair Value, Less Than 12 Months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Short-term investment maturity period range start.
Short Term Investment Maturity Period Range Start
Short term investments, maturity start range
Public equity offering.
Public Equity Offering Policy [Text Block]
Public Equity Offerings
November 2016 placement.
November 2016 Placement
November2016 Placement [Member]
Assets
Total assets
Derivative Contract [Domain]
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of preferred shares to common stock
June 2020 Public Offering
June Twenty Twenty Public Equity Offering [Member]
September Twenty Twenty public equity offering member
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Earnings Per Share, Diluted
Risks and uncertainties.
Risks And Uncertainties Policy [Text Block]
Risks and Uncertainties
Trailing stock price per share.
Trailing Stock Price Per Share
Ten-trading day trailing average common stock price
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Balance at the end of the period
Balance at the beginning of the period
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Document Fiscal Period Focus
Document Fiscal Period Focus
Restrictions on Cash and Cash Equivalents [Table Text Block]
Reconciliation of Cash, Cash Equivalents, and Restricted Cash
Increase (Decrease) in Accounts Receivable
Accounts receivable
Preferred stock, $0.001 par value; authorized shares-5,000,000 at September 30, 2022 and December 31, 2021; Class A Convertible Preferred shares issued and outstanding-2,794,549 at September 30, 2022 and December 31, 2021
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Collaborative arrangement first-year research and development fees prepayment.
Collaborative Arrangement First Year Research And Development Fees Prepayment
First-year research and development fees prepayment
Information of sale of stock.
Sale Of Stock [Axis]
Sale Of Stock
Investment Income, Interest
Interest income
Common Stock issued during period value private placement.
Common Stock Issued During Period Value Private Placement1
Private placement of common stock, net of issuance costs
Counterparty Name [Domain]
Counterparty Name
Milestone Three Member.
Milestone Three [Member]
Milestone Three
Other Nonoperating Income
Other income:
Operating Lease, Liability
Total lease liability
Operating Lease, Liability, Total
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-Average Grant Date Fair Value per Share
Short-Term Debt, Type [Axis]
Short-term Debt, Type
Sensitivity percentage increase/decrease in stock price used as an input to measure fair value.
Fair Value Inputs Stock Price Sensitivity Percentage Increase Decrease
Sensitivity analysis fair value inputs stock price increase/decrease
Statement of Financial Position [Abstract]
Debt Security, Government, Non-US [Member]
Non-U.S. government securities
Entity File Number
Entity File Number
Janssen agreement.
Janssen Agreement [Member]
Janssen Agreement
Statement of Cash Flows [Abstract]
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Thereafter
Proceeds from Sale, Maturity and Collection of Investments
Maturities of investments
Proceeds from Sale, Maturity and Collection of Investments, Total
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Number of shares to be purchased
Fair value liabilities level 3 to level 1 transfers amount.
Fair Value Liabilities Level3 To Level1 Transfers Amount
Transfer of liabilities from level 3 to level 1
Statistical Measurement [Domain]
Statistical Measurement
Sale of Stock
Sale of Stock [Axis]
Fair value liabilities level 1 to level 3 transfers amount.
Fair Value Liabilities Level1 To Level3 Transfers Amount
Transfer of liabilities from level 1 to level 3
Class of Stock [Domain]
Class of Stock
Unrealized Gains
Debt Securities, Available-for-Sale, Unrealized Gain
Stock price appreciation milestone, liability
Stock Price Appreciation Milestone Liability
Stock price appreciation milestone liability.
Amortization of sub license consideration.
Amortization Of Sub License Consideration
Amortization of sublicense consideration
Legal Entity [Axis]
Legal Entity
Lease, Cost [Table Text Block]
Schedule of Components of Lease Expense
Collaborative arrangement annual payments receivable recorded under deferred revenue.
Collaborative Arrangement Annual Payments Receivable Recorded Under Deferred Revenue
Collaborative arrangement annual payments receivable recorded as deferred revenue
Stock issued during period value collaboration partner.
Stock Issued During Period Value Collaboration Partner
Issuance of stock to collaboration partner, net of issuance costs
Subsequent Events [Abstract]
Fair Value Disclosures [Text Block]
Fair Value Measurements
Transfer of assets from level 2 to level 1
Transfer of assets from level 2 to level 1
Transfer of assets from level 2 to level 1
Proceeds from Stock Options Exercised
Issuance of common stock from equity incentive plans, net of issuance costs
Proceeds from Issuance of Common Stock
Proceeds from public offering of common stock, net of issuance costs
Proceeds from public offering of common stock, net of issuance costs
Lease Agreements [Member]
The Premises 2020 Lease Agreement
Other Comprehensive Income (Loss), Tax [Abstract]
Other comprehensive income (loss):
Contract With Customer, Milestone Receivable Recorded to Deferred Revenue.
Contract With Customer Milestone Receivable Recorded To Deferred Revenue
Milestone receivable to deferred revenue
Period to treat award as grant, if award not treated as loan.
Period To Treat Award As Grant If Award Not Treated As Loan
Period to treat award as grant, if award not treated as loan
Antidilutive Securities [Axis]
Antidilutive Securities
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value (in dollars per share)
Contract with Customer, Liability, Current
Deferred revenue, current portion
first Janssen Cancer Target
First Janssen Cancer Target [Member]
First Janssen Cancer Target
Capitalized Contract Cost, Amortization
Amortization of collaboration contract assets
Lessee, Lease, Description [Line Items]
Lessee Lease Description [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration agreement
Stock price appreciation milestones.
Stock Price Appreciation Milestones Policy [Text Block]
Stock Price Appreciation Milestones
Cash received upon achievement of each milestone.
Cash Received Upon Achievement Of Each Milestone
Cash received upon achievement of each milestone
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted
Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block]
Organization and Summary of Significant Accounting Policies
Finite-Lived Intangible Assets, Major Class Name [Domain]
Finite-Lived Intangible Assets, Major Class Name
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to unvested restricted shares
Corporate Debt Securities [Member]
Corporate debt securities
General and Administrative Expense [Member]
General And Administrative
Convertible Preferred Stock, Shares Issued upon Conversion
Number of shares to be issued upon conversion
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to outstanding options
Commercial Paper [Member]
Commercial Paper
Current Fiscal Year End Date
Current Fiscal Year End Date
Investment Type [Axis]
Investment Type
Liability Class [Axis]
Liability Class
Financial Instruments [Domain]
Financial Instruments
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash, cash equivalents and restricted cash at end of the period
Cash, cash equivalents and restricted cash at beginning of the period
Total cash, cash equivalents, and restricted cash shown in the unaudited condensed consolidated statement of cash flows
Accrued clinical trial related costs current.
Accrued Clinical Trial Related Costs Current
Accrued clinical trial related costs
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Entity Address, Address Line One
Entity Address, Address Line One
Finite-Lived Intangible Assets by Major Class [Axis]
Finite-Lived Intangible Assets by Major Class
Accrued Liabilities, Current [Abstract]
Current accrued expenses
Warrants exercise terms description.
Warrants Exercise Terms Description
Terms of exercise
Investment, Policy [Policy Text Block]
Investments
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Investments
Represents an arrangement whereby both an employee and a non-employee is entitled to receive in the future, subject to vesting and other restrictions, certain number of shares in the entity at a specified price, as defined in the agreement.
Employee And Non Employee Stock Option [Member]
Employee And Non Employee Stock Option
Stock price decreased by ten percent per share.
Stock Price Decreased By Ten Percent Per Share [Member]
Stock price decreased by 10% per share
Restricted Cash, Noncurrent
Restricted cash
Preferred Stock, Shares Issued
Preferred stock, issued shares
Preferred Stock, Shares Issued, Total
Balance Sheet Location [Domain]
Balance Sheet Location
Other Accrued Liabilities, Current
Accrued other
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Purchase price of prefunded warrants.
Purchase Price Of Prefunded Warrants
Purchase price of prefunded warrants
Johnson & Johnson Innovation-JJDC, Inc.
Johnson Johnson Innovation J J D C Inc [Member]
Johnson Johnson Innovation J J D C Inc
Research services.
Research Services [Member]
Research services
Collaborative Arrangement [Member]
Collaborative Arrangement
Stock Issued During Period, Shares, New Issues
Issuance of common stock in conjunction with public offering (in shares)
Common stock issued
CIRM award liability, noncurrent.
C I R M Award Liability Noncurrent
CIRM award liability, net of current portion
Fair Value Assumptions Expected Term 1.
Fair Value Assumptions Expected Term1
Estimated term (in years)
Sale Of Stock [Domain].
Sale Of Stock [Domain]
Sale Of Stock
Assets, Fair Value Disclosure [Abstract]
Financial assets:
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Equity [Abstract]
Employee Retention Credit Policy
Employee Retention Credit Policy
Employee Retention Credit
Milestone receivable due
Contract with Customer, Liability, Revenue Recognized
Total cash received upon achievement of milestone
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Cancelled
Operating Income (Loss)
Loss from operations
Debt Instrument, Interest Rate, Stated Percentage
Award considered as a loan, interest rate
Lessee, Operating Lease, Option to Extend
Lessee, operating lease, option to extend
Equity premium.
Equity Premium
Equity premium
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Estimated Fair Value, Total
Debt Securities, Available-for-Sale, Unrealized Loss Position
Class of Warrant or Right [Domain]
Class of Warrant or Right
Entity Filer Category
Entity Filer Category
Stock purchase agreement [Member].
Stock Purchase Agreement [Member]
Stock Purchase Agreement
Operating Expenses
Total operating expenses
Fair Value by Liability Class [Domain]
Fair Value by Liability Class
Entity Current Reporting Status
Entity Current Reporting Status
Stock Issued During Period, Value, Restricted Stock Award, Gross
Issuance of common stock upon vesting of restricted stock units
Asset Class [Domain]
Asset Class
Revenue Recognition, Milestone Method, Revenue Recognized
Total cash received upon achievement of milestone
Stockholders' Equity Note Disclosure [Text Block]
Convertible Preferred Stock and Stockholders’ Equity
Stockholders' Equity Attributable to Parent
Balance
Balance
Total stockholders’ equity
Unrealized Losses, Total
Unrealized Losses, Total
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Debt Securities, Available-for-Sale, Realized Gain (Loss)
Available-for-sale securities, realized gains (losses) on sales
Debt Securities, Available-for-sale, Realized Gain (Loss), Total
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Gain (Loss)
Short-Term Investments [Member]
Short-term Investments [Member]
Asset Class [Axis]
Asset Class
Milestone Two Member.
Milestone Two [Member]
Milestone Two
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location [Axis]
Income Statement Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Cancelled
Common stock, $0.001 par value; authorized shares-250,000,000 at September 30, 2022 and December 31, 2021; issued and outstanding-96,862,797 at September 30, 2022 and 95,726,962 at December 31, 2021
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
Unrealized gain (loss) on available-for-sale securities, net
Equity Components [Axis]
Equity Components
Maximum percentage of common stock ownership together with affiliates allowable after exercise of prefunded warrants.
Maximum Percentage Of Common Stock Ownership Together With Affiliates Allowable After Exercise Of Prefunded Warrants
Maximum percentage of common stock ownership together with affiliates allowable after exercise of prefunded warrants
Leases [Abstract]
Contract with Customer, Liability
Milestone payments recorded to deferred revenue
Contract with Customer, Liability, Total
Milestone payments during the period.
Milestone Payments
Stock price appreciation milestone payment (in millions)
Milestone payments
Convertible preferred stock and stockholders' equity.
Convertible Preferred Stock And Stockholders Deficit Disclosure [Abstract]
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Accounts payable and accrued expenses
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Entity Emerging Growth Company
Entity Emerging Growth Company
Related Party Transaction [Axis]
Related Party Transaction
Unrealized Losses, 12 Months or Greater
Unrealized Losses, 12 Months or Greater
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
Operating Expenses [Abstract]
Operating expenses:
Ono Pharmaceutical Company Ltd.
Ono Pharmaceutical Company Ltd [Member]
Ono Pharmaceutical Co. Ltd
Revenue [Policy Text Block]
Revenue Recognition
Schedule of Stock by Class [Table]
Schedule Of Stock By Class [Table]
Letter of Credit [Member]
Letter of Credit
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Contract with Customer, Liability, Cumulative Catch-up Adjustment to Revenue, Change in Estimate of Transaction Price
Milestone receivable with increase in initial transaction price
Lessee, Operating Lease, Liability, to be Paid [Abstract]
Payments to Acquire Investments
Purchases of investments
Payments to Acquire Investments, Total
Debt Securities, Available-for-Sale [Table]
Document Transition Report
Document Transition Report
Assets, Fair Value Disclosure
Financial assets/ Non-financial assets
Total financial assets measured at fair value on a recurring basis
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Granted
Depreciation, Depletion and Amortization
Depreciation and amortization
Depreciation, Depletion and Amortization, Total
Represents the amount of upfront payments received under collaborative arrangements is recorded as deferred revenue.
Collaborative Arrangements Upfront Payments Recorded Under Deferred Revenue
Non-refundable upfront payments recorded as deferred revenue
Sale of Stock, Price Per Share
Common stock per share
Collaborative Arrangement Disclosure [Text Block]
Collaboration and License Agreements
Straight-line lease expense.
Straight Line Lease Expense
Straight-line lease expense
CIRM award liability current.
C I R M Award Liability Current
CIRM award liability, current portion
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Number of Restricted Stock Units
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Additional Cancer Targets.
Additional Cancer Targets [Member]
Additional Cancer Targets
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Preferred stock conversion price.
Preferred Stock Conversion Price
Conversion price
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Operating Lease, Liability, Current
Operating lease liabilities, current portion
Number of disbursements receivable based on completion of certain operating milestones.
Number Of Disbursements Receivable Based On Completion Of Certain Operating Milestones
Number of disbursements receivable based on completion of certain operating milestones
Additional Paid-in Capital [Member]
Additional Paid In Capital
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Maximum percentage of common stock ownership after change upon notice.
Maximum Percentage Of Common Stock Ownership After Change Upon Notice
Maximum percentage of common stock ownership after change upon notice
Fair value liabilities level 2 to level 3 transfers amount.
Fair Value Liabilities Level2 To Level3 Transfers Amount
Transfer of liabilities from level 2 to level 3
Redmile Group, LLC and Affiliates.
Redmile Group Limited Liability Company And Affiliates [Member]
Redmile Group, LLC and Affiliates
Prepaid expenses and other assets.
Prepaid Expenses And Other Assets [Member]
Prepaid Expenses And Other Assets
Entity Registrant Name
Entity Registrant Name
Liabilities, Fair Value Disclosure
Total financial liabilities measured at fair value on a recurring basis
Liabilities, Fair Value Disclosure, Total
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of weighted-average assumptions used to determine the fair value of employee and nonemployee stock option grants
Class of Stock [Axis]
Class of Stock
Lessee, Lease, Description [Table]
Lessee Lease Description [Table]
Award agreement for research and development disclosure.
Award Agreement For Research And Development Disclosure [Text Block]
California Institute for Regenerative Medicine Award
Pre-Funded Warrants.
Pre Funded Warrants [Member]
Pre-Funded Warrants
Property, Plant and Equipment, Net
Property and equipment, net
Property, Plant and Equipment, Net, Total
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Award Type [Domain]
Award Type
Statement [Line Items]
Statement [Line Items]
Other Income
Liabilities, Fair Value Disclosure [Abstract]
Financial liabilities:
Temporary Equity, by Class of Stock [Table]
Temporary Equity By Class Of Stock [Table]
Title of 12(b) Security
Title of 12(b) Security
Stock price appreciation milestone.
Stock Price Appreciation Milestones [Member]
Stock price appreciation milestones
Common Stock [Member]
Common Stock
Sale of Stock, Consideration Received on Transaction
Net proceeds from issuance of shares after related cash costs
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Cash, Cash Equivalents and Restricted Cash
Net Cash Provided by (Used in) Operating Activities [Abstract]
Operating activities
Equity Component [Domain]
Equity Component
Convertible Preferred Stock [Member]
Class A Convertible Preferred Shares
Class A Convertible Preferred Stock
Revenue from Contract with Customer, Excluding Assessed Tax
Collaboration revenue
Revenue recognized
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Debt instrument repayment phase four rate.
Debt Instrument Repayment Phase Four Rate [Member]
Loan Repayment Rate Four
Entity Address, State or Province
Entity Address, State or Province
2026
Lessee, Operating Lease, Liability, to be Paid, Year Four
Upfront fee.
Upfront Fee [Member]
Upfront Fee
Collaborative arrangement percentage of reduction on milestone payments.
Collaborative Arrangement Percentage Of Reduction On Milestone Payments
Percentage of reduction on milestone payments
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net change in cash, cash equivalents and restricted cash
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest
Comprehensive loss
Document Type
Document Type
Proceeds from Collaborators
Receipt of first disbursement under the Award
Sensitivity analysis share price fair value input.
Share Price Fair Value Input
Sensitivity analysis share price fair value input
Entity Shell Company
Entity Shell Company
Share-Based Payment Arrangement, Expense
Stock-based compensation
Total stock-based compensation expense
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Available For Sale Debt Securities Amortized Costs Basis
Available For Sale Debt Securities Amortized Costs Basis
Security Exchange Name
Security Exchange Name
Class of Stock [Line Items]
Class Of Stock [Line Items]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Schedule of milestone payments valuation assumptions table text block.
Schedule Of Milestone Payments Valuation Assumptions Table [Text Block]
Schedule of Determine the Estimated Fair Value of the Stock Price Appreciation Milestones Payments
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Expected recognition weighted average period of unrecognized compensation cost
Award from regenerative medicine institute.
Award From Regenerative Medicine Institute [Table]
Award From Regenerative Medicine Institute [Table]
Operating Lease, Cost
Total operating lease expense
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs)
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Schedule of Future Minimum Payments Under Non-cancelable Operating Leases
Consolidation, Policy [Policy Text Block]
Principles of Consolidation
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of restricted stock unit activity under the Plan
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Issued Accounting Pronouncements
Debt instrument repayment phase three rate.
Debt Instrument Repayment Phase Three Rate [Member]
Loan Repayment Rate Three
Common Stock, Shares, Outstanding
Common stock, outstanding shares
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Profit loss sharing percentage.
Profit Loss Sharing Percentage
Profits and losses sharing percentage
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion and amortization of premiums and discounts on investments, net
Fair Value, Inputs, Level 2 [Member]
Significant Other Observable Inputs (Level 2)
Deferred Revenue, Current
Deferred revenue classified as current
Deferred Revenue, Current, Total
Investment
Debt Securities, Available-for-Sale
Estimated Fair Value
Debt Securities, Available-for-sale, Total
Net Cash Provided by (Used in) Investing Activities [Abstract]
Investing activities
Commitments and Contingencies
Commitments and contingencies
Common Stock, Shares, Issued
Common stock issued
Common Stock, Shares, Issued, Total
US Treasury Securities [Member]
U.S. Treasury debt securities
Treasuries, Non-U.S. Government Securities, Municipal Securities, Corporate Debt Securities and Commercial Paper
Variable Rate [Domain]
Variable Rate
Minimum [Member]
Minimum
Common stock of public offering and issuance of pre funded warrants.
Common Stock Of Public Offering And Issuance Of Pre Funded Warrants
Public offering of common stock and issuance of pre-funded warrants, net of issuance costs(in shares)
Stock price appreciation milestone payable.
Stock price appreciation milestone payable
Stock Price Appreciation Milestone Payable
Milestone one member.
Milestone One [Member]
Milestone One
Lessee, Leases [Policy Text Block]
Leases
Accrued Liabilities, Current
Accrued expenses
Total current accrued expenses
Debt Instrument [Axis]
Debt Instrument
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders’ equity:
Schedule of Available-for-Sale Securities [Table]
Schedule Of Available For Sale Securities [Table]
Counterparty Name [Axis]
Counterparty Name
Entity Address, Address Line Two
Entity Address, Address Line Two
Restricted Cash and Cash Equivalents, Noncurrent
Restricted cash
Restricted Cash and Cash Equivalents, Noncurrent, Total
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Cancelled
Enterprise Value Milestones Liability At Fair Value.
Enterprise Value Milestones Liability At Fair Value
Enterprise value milestones liability at fair value
Award Type [Axis]
Award Type
Related Party Transaction [Domain]
Related Party Transaction
Other Nonoperating Income (Expense)
Total other income (expense)
Pre Funded Common Stock Warrant
Pre Funded Common Stock Warrant [Member]
Pre funded common stock warrant Member.
Nonoperating Income (Expense) [Abstract]
Other income:
Research and Development Expense
Research and development
Research and Development Expense, Total
Lessee, Operating Lease, Liability, to be Paid
Future minimum payments under the operating leases
Total undiscounted lease payments
Enterprise value milestone payments contingent consideration.
Enterprise Value Milestone Payments Contingent Consideration
Enterprise value milestone payments contingent consideration
Lessee, Operating Lease, Term of Contract
Lease term
Additional candidate milestone payment.
Additional Candidate Milestone Payment
Additional candidate milestone Payments
Entity Central Index Key
Entity Central Index Key
Stock purchase agreement axis.
Stock Purchase Agreement [Axis]
Stock Purchase Agreement
Award from regenerative medicine institute.
Award From Regenerative Medicine Institute [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Weighted-average assumptions to determine fair value of stock options
Investments, Debt and Equity Securities [Abstract]
Debt Securities, Available-for-Sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Interest Receivable
Accured Interest on investments
Aggregated by investment category and the length of time
Investment Holdings, Schedule of Investments [Table Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Addtional amount available for funding under award.
Addtional Amount Available For Funding Under Award
Additional amount available for funding under award
Short-term investments and related maturity receivables.
Short Term Investments And Related Maturity Receivables
Short-term investments and related maturity receivables
Measurement Frequency [Axis]
Measurement Frequency
Equity premium on share price per share under agreement.
Equity Premium On Share Price Per Share Under Agreement
Equity premium per share
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
Increase Decrease in fair value of enterprise value milestones
Increase Decrease In Fair Value Of Enterprise Value Milestones
Change in fair value of enterprise value milestones
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization and summary of significant accounting policies
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Balance at the end of the period
Balance at the beginning of the period
Preferred Class A [Member]
Non-Voting Class A Preferred Stock
Research and Development Expense [Member]
Research And Development
Fair Value, Nonrecurring [Member]
Fair Value Measurements Nonrecurring
Public offering of common stock and issuance of pre-funded warrants.
Public Offering Of Common Stock And Issuance Of Pre Funded Warrants
Public offering of common stock and issuance of pre-funded warrants, net of issuance costs
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right-of use assets obtained in exchange for lease obligations
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Retained Earnings [Member]
Accumulated Deficit
Candidate one.
Candidate One [Member]
Candidate 1
Stock price appreciation milestones.
Stock Price Appreciation Milestones
Stock price appreciation milestones
Money Market Funds [Member]
Money market funds
Aggregate equity premium on shares issued under agreement.
Aggregate Equity Premium On Shares Issued Under Agreement
Aggregate equity premium on shares
Stock price increased by ten percent per share.
Stock Price Increased By Ten Percent Per Share [Member]
Stock price increased by 10% per share
Common stock issued during period shares private placement.
Common Stock Issued During Period Shares Private Placement1
Private placement issuances of common stock, net of offering costs (in shares)
Disclosure of accounting policy for private placement of common stock.
Private Placement Of Common Stock Policy Policy [Text Block]
Private Placements of Common Stock
Percentage of Tax Credit
Percentage of Tax Credit
Percentage of tax credit
Transfer of assets from level 1 to level 2
Transfer of assets from level 1 to level 2
Transfer of assets from level 1 to level 2
Additional Paid in Capital
Additional paid-in capital
Additional Paid in Capital, Total
Additional Paid in Capital, Beginning Balance
Additional Paid in Capital, Ending Balance
Entity Interactive Data Current
Entity Interactive Data Current
Debt instrument repayment phase two rate.
Debt Instrument Repayment Phase Two Rate [Member]
Loan Repayment Rate Two
Letters of Credit Outstanding, Amount
Letters of credit outstanding amount
Temporary Equity [Line Items]
Convertible preferred stock
Sublicense consideration.
Sublicense Consideration [Member]
Sublicense Consideration
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental schedule of noncash investing and financing activities
2023
Lessee, Operating Lease, Liability, to be Paid, Year One
Estimated Fair Value, 12 Months or Greater
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Proceeds from issuance of pre-funded warrants, net of issuance costs
Proceeds from Issuance of Warrants
Local Phone Number
Local Phone Number
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Schedule of Assets Measured at Fair Value on Recurring Basis
Basis of Accounting, Policy [Policy Text Block]
Unaudited Interim Financial Information
Percentage of common stock ownership upon preferred stock conversion.
Percentage Of Common Stock Ownership Upon Preferred Stock Conversion
Percentage of common stock ownership upon preferred stock conversion
Lessee, Operating Lease, Existence of Option to Extend [true false]
Lessee, operating lease, existence of option to extend
Corresponding asset for sublicense consideration paid.
Corresponding Asset For Sublicense Consideration Paid
Sublicense consideration paid
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted
Contract with customer asset to receivable.
Contract With Customer Asset To Receivable
Milestone receivable
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Summary of Changes in the Fair Value of the Company's Level 3 Enterprise Fair Value Milestone Payment Liability
Fair Value Measurement Inputs and Valuation Techniques [Abstract]
Determine the estimated fair value of the enterprise value milestone payments
Other Current Assets [Member]
Current Assets [Member]
Enterprise value milestone payment.
Enterprise Value Milestone Payment
Enterprise value milestone payment
Income Statement Location [Domain]
Income Statement Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Balance at the end of the period
Balance at the beginning of the period
Proceeds From Research and Development Fees Received.
Proceeds From Research And Development Fees Received
Research and development fees cash payments received
Award from the california institute for regenerative medicine.
Award From California Institute For Regenerative Medicine [Abstract]
Shares, Outstanding
Balance (in shares)
Balance (in shares)
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Balance at the end of the period
Balance at the beginning of the period
Share Price
Closing stock price as of re measurement date
Debt Instrument, Name [Domain]
Debt Instrument, Name
Document Fiscal Year Focus
Document Fiscal Year Focus
Common stock multiples and the enterprise value milestone payments.
Common Stock Multiples And The Enterprise Value Milestone Payments Table [Text Block]
Summary of all Possible Stock Price Appreciation Milestone Payments
Class of Warrant or Right [Axis]
Class of Warrant or Right
Award for first-in-human clinical trial.
Award For First In Human Clinical Trial
Award for first-in-human clinical trial
2024
Lessee, Operating Lease, Liability, to be Paid, Year Two
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Earnings Per Share, Basic
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted-Average Price
Assets [Abstract]
Assets
Employee Retention Credit [Member]
Employee Retention Credit [Member]
Employee Retention Credit
Refundable Tax Credit
Refundable Tax Credit
Refundable tax credit
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Shares Issued, Price Per Share
Share issue price (in dollars per share)
Share-Based Payment Arrangement [Member]
Common Stock Options
Financial Instrument [Axis]
Financial Instrument
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Number of Options
Debt instrument repayment phase one rate.
Debt Instrument Repayment Phase One Rate [Member]
Loan Repayment Rate One
Liabilities and Equity [Abstract]
Liabilities and Stockholders’ Equity
Stock purchase agreement domain.
Stock Purchase Agreement [Domain]
Stock Purchase Agreement
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Preferred Stock
Preferred Stock [Member]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Award from regenerative medicine institute.
Award From Regenerative Medicine Institute [Line Items]
Award from California institute for regenerative medicine
Assets, Current [Abstract]
Current assets:
Class of Warrant or Right, Exercise Price of Warrants or Rights
Exercise price of warrants
Unrealized Losses, Less Than 12 Months
Unrealized Losses, Less Than 12 Months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Payables and Accruals [Abstract]
Measurement Frequency [Domain]
Measurement Frequency
Fair Value Assumptions Risk Free Interest Rate 1.
Fair Value Assumptions Risk Free Interest Rate1
Risk-free interest rate
Upfront fee and equity premium.
Upfront Fee And Equity Premium [Member]
Upfront Fee and Equity Premium
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Lease, Cost [Abstract]
Entity [Domain]
Entity
Convertible preferred stock.
Convertible Preferred Stock Policy [Text Block]
Convertible Preferred Stock
Increase decrease in fair value of stock price appreciation milestones.
Increase Decrease In Fair Value Of Stock Price Appreciation Milestones
Change in fair value of stock price appreciation milestones
Change in fair value of stock price appreciation milestones
Accrued Salaries, Current
Accrued payroll and other employee benefits
Cover [Abstract]
Other-than-temporary Impairment Loss, Debt Securities, Available-for-Sale
Available-for-sale securities, impairment
Other-than-temporary Impairment Loss, Debt Securities, Available-for-sale, Total
Product and Service [Domain]
Product and Service
2027
Lessee, Operating Lease, Liability, to be Paid, Year Five
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested
Contract With Customer Asset Noncurrent
Contract With Customer Asset Noncurrent
Liabilities, Current [Abstract]
Current liabilities:
Stock issued during period shares for private placement
Stock Issued During Period Shares For Private Placement
Issuance of common stock during period for private placements (in shares)
Percentage of common stock ownership for preferred stock conversion change upon notice.
Percentage Of Common Stock Ownership For Preferred Stock Conversion Change Upon Notice
Preferred shares converted into common stock percentage of ownership change upon notice
Maximum [Member]
Maximum
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized gain (loss) on investments
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of allocation of stock-based compensation for all stock awards
Net Cash Provided by (Used in) Investing Activities
Net cash provided by (used in) investing activities
Proceeds from public offering of common stock and issuance of pre-funded warrants, net of issuance costs
Proceeds from Public Offering of Common Stock and Issuance of Pre-Funded Warrants
The cash inflow associated with the amount received.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of stock options, net of issuance costs (in shares)
Exercised
Fair Value, Inputs, Level 3 [Member]
Significant Unobservable Inputs (Level 3)
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Issuance of common stock upon vesting of restricted stock units (in shares)
Collaborative arrangement aggregate milestone payments receivable.
Collaborative Arrangement Aggregate Milestone Payments Receivable
Aggregate milestone payments
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options, net of issuance costs
Long-Term Investments
Long-term investments
Long-term Investments, Total
Preferred Stock, Convertible, Terms
Terms of conversion
Common Stock, Shares Authorized
Common stock, authorized shares
Short-Term Debt, Type [Domain]
Short-term Debt, Type
Trading Symbol
Trading Symbol
Schedule of Stock Options Roll Forward [Table Text Block]
Summary of stock option activity under the Plan
Schedule of Stockholders Equity [Table Text Block]
Summary of changes in stockholders' equity
Debt Securities, Available-for-Sale [Table Text Block]
Summary of Investments
Municipal Notes [Member]
Municipal securities
Title of Individual [Domain]
Title of Individual
Upfront, non-refundable and non-creditable payment.
Upfront Non Refundable And Non Creditable Payment
Upfront, non-refundable and non-creditable payment
Balance Sheet Location [Axis]
Balance Sheet Location
FT516.
F T Five One Six [Member]
FT516
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Unrealized Losses
Accrued milestone payment under the Amended MSK License
Accrued Milestone Payment Under The Amended MSK License Current
Accrued milestone payment under the amended MSK license current.
Plan Name [Axis]
Title of Individual [Axis]
Title of Individual
Stock issued during period shares collaboration partner.
Stock Issued During Period Shares Collaboration Partner
Issuance of stock to collaboration partner, net of issuance costs (in shares)
Common Stock, Par or Stated Value Per Share
Common stock, par value (in dollars per share)
Number of disbursements.
Number Of Disbursements
Number of disbursements
Short-term investment maturity period range end.
Short Term Investment Maturity Period Range End
Short term investments, maturity end range
Variable Lease, Cost
Variable lease expense
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Derivative Instrument [Axis]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Potentially dilutive securities (in shares)
Cash and Cash Equivalents, Fair Value Disclosure
Money market funds
Collaborative arrangement potential additional milestones.
Collaborative Arrangement Potential Additional Milestones
Collaborative arrangement potential additional milestones